Active Self-Experiment

Personalized protocol testing with real-world physiological signals.

Blueprint: Caffeine Timing Blueprint
Phase: Intervention (Day 6 of 14)
Data Completeness: 86%
Evidence Confidence: Moderate

Active Blueprint

Structured protocol testing with real-world physiological signals.

Blueprint Overview

Caffeine Timing Blueprint
Clinical intent:
Reduce circadian disruption and sympathetic overactivation.
Duration:
14 days (locked)
Intervention:
  • First caffeine ≥90 min after waking
  • Last caffeine ≥9 h before sleep
Expected adaptation window:
5–10 days

Signals Being Measured

Sleep Onset Latency (minutes)
Why it matters: Time to fall asleep reflects nervous system arousal and caffeine clearance.
Nocturnal Fragmentation Index
Why it matters: Frequent awakenings indicate disrupted sleep architecture.
Daytime Alertness Score
Why it matters: Measures whether sleep changes improve real-world energy.
Autonomic Balance (HRV)
Why it matters: Higher HRV suggests better stress recovery and parasympathetic tone.

Data Sources

Wearable sleep tracking (duration + awakenings)
Morning subjective check-in (1–10)
Caffeine timing log (yes/no compliance)
Status: Connected

Compliance & Adherence

Protocol adherence: 92%
Missed caffeine cutoff: 1 day
Notes flagged: 2

Early Signal Trends

Sleep latency:↓ 18%
Night awakenings:↓ 1.2/night
HRV (7-day avg):↑ 9%
Afternoon crash severity:
Signals emerging — not yet conclusive

Investigator Notes

Adjunct Protocols (Held Constant During Experiment)

These variables are held constant to isolate causal effects.

SupplementDoseTimingPurposeStatus
Magnesium glycinate
400 mgEveningSleep supportStable
Omega-3
2 gWith mealsInflammation controlStable

Risk-Focused Micro-Plans

Adaptive intelligence that activates when specific risk thresholds are met.

Sleep Disruption Risk

Trigger

Sleep efficiency <85% for 3 consecutive nights

Auto-Activated Actions
  • Advance caffeine cutoff by 60 min
  • Add 10 min NSDR post-lunch
  • Evening light dimming protocol
Expected Benefit

Stabilize sleep architecture and reduce sleep debt accumulation.

Red Flags & Action Thresholds

Clear guidelines for when to monitor, retest, or seek medical attention based on signal changes.

Autonomic Stress Load

When to Monitor
  • • HRV ↓ >20% from baseline for 5 days
  • • Resting HR ↑ >10 bpm from baseline
When to Retest

After 7–10 days of protocol adjustment

When to Seek Review

Persistent fatigue, palpitations, or sleep fragmentation